| 000 -LEADER |
|---|
| fixed length control field |
03369nam a22003497a 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20150712005503.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
120430s2012 gw a b 001 0 eng d |
| 016 7# - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER |
|---|
| Record control number |
015904442 |
| Source |
Uk |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9783527331291 |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
BTCTA |
| Language of cataloging |
eng |
| Transcribing agency |
BTCTA |
| Modifying agency |
UKMGB |
| -- |
YDXCP |
| -- |
CDX |
| -- |
BDX |
| -- |
VGM |
| -- |
OHX |
| -- |
DLC |
| 042 ## - AUTHENTICATION CODE |
|---|
| Authentication code |
lccopycat |
| 060 ## - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
|---|
| Item number |
M H |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
R |
| Source |
lcco |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
615.1901 |
| 084 ## - OTHER CLASSIFICATION NUMBER |
|---|
| Classification number |
615.1901 |
| Item number |
M H |
| 001 - CONTROL NUMBER |
|---|
| control field |
0000086968 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
0000 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mascher, Hermann. |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
HPLC methods for clinical pharmaceutical analysis |
| Medium |
[[Book] :] |
| Remainder of title |
a user's guide / |
| Statement of responsibility, etc. |
Hermann Mascher. |
| 250 ## - EDITION STATEMENT |
|---|
| Edition statement |
1st ed. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc. |
Weinheim : |
| Name of publisher, distributor, etc. |
Wiley-VCH, |
| Date of publication, distribution, etc. |
c2012. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
ix, 247 p. : |
| Other physical details |
ill. ; |
| Dimensions |
25 cm. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc |
Includes bibliographical references and index. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
1.Introduction -- 1.1.First Question: Determination of Ibuprofen in Plasma -- 1.2.Second Question: Determination of Tryptophan in Urine -- 1.3.Third Question: Determination of Paclitaxel in Tissue -- 2.Planning of Analyses -- 2.1.Introduction -- 2.2.Limit of Detection (LOD) and Determination (LLOQ) -- 2.3.Detectors -- 2.4.Structure of the Analyte -- 2.5.Solubility of an Analyte -- 2.6.Selection of the Detector -- 3.Sample Preparation -- 3.1.Dilution -- 3.2.Protein Precipitation, Overview -- 3.3.Extraction -- 4.HPLC Separation -- 4.1.HPLC Pumps -- 4.2.Degasser -- 4.3.Injector -- 4.4.HPLC Columns -- 5.Detection -- 5.1.Detection in the Pharmaceutical/Bioanalytical Area -- 5.2.Detection in the "Clinical Area" (Therapy Control/Compliance) -- 6.Chemical Derivatization for Detection Enhancement -- 7.Validation Concepts -- 7.1.Introduction -- 7.2.Realization of the FDA Guideline -- 8.Practical Hints Concerning Stability, Destruction and Degradation Products -- 9.Metabolites -- 10.Internal Standards -- 11.Case Studies with Intensive Discussion for Each Substance -- 11.1.Acetylcarnitine in Plasma -- 11.2.Acetylcysteine in Plasma -- 11.3.Acyclovir in Plasma and Urine -- 11.4.Caffeine in Plasma -- 11.5.Diazepam in Plasma -- 11.6.Diclofenac in Plasma -- 11.7.Dihydralazine in Plasma -- 11.8.Duramycin (Moli1901) in Plasma -- 11.9.Fluticasone Propionate in Plasma -- 11.10.Hydroxytriamterene Sulfate and Triamterene in Plasma and Urine -- 11.11.Ibuprofen in Plasma (also Enantiomeric Separation) -- 11.12.Minocycline in Plasma -- 11.13.Norfloxacine in Plasma and Urine -- 11.14.Paclitaxel in Plasma, Urine and Tissue -- 11.15.Paracetamol (Acetaminophen) in Plasma -- 11.16.Pimelic Acid in Plasma and Urine -- 11.17.8-Prenylnaringenin in Plasma and Different Types of Tissues -- 11.18.Silibinin in Plasma -- 11.19.Valnemulin in Plasma, Different Tissue Types and in Animal Feed -- 11.20.Vitamin B1 (Total Thiamine) in Plasma -- Table 11.1 Recommended books -- Table 11.2 Properties of substances -- Appendix -- Short Description of Determination for about 100 Substances -- Substances listed in the Appendix. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
High performance liquid chromatography. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Drugs |
| General subdivision |
Analysis. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Pharmaceutical technology. |
| 856 42 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Materials specified |
Contributor biographical information |
| Uniform Resource Identifier |
http://www.loc.gov/catdir/enhancements/fy1210/2012392592-b.html |
| 856 42 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Materials specified |
Publisher description |
| Uniform Resource Identifier |
http://www.loc.gov/catdir/enhancements/fy1210/2012392592-d.html |
| 856 41 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Materials specified |
Table of contents only |
| Uniform Resource Identifier |
http://www.loc.gov/catdir/enhancements/fy1210/2012392592-t.html |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Books |
