| 000 -LEADER |
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| fixed length control field |
02540nam a22002417a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
180912s2018 ua ||||g bm|| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Transcribing agency |
SOUL |
| 041 ## - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
ara |
| Language code of original |
eng |
| 082 40 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Edition number |
21 |
| Classification number |
572 |
| Item number |
G P |
| 100 #1 - MAIN ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
4552 |
| Personal name |
Muhamad, Suzan Shawky Abuel-kasem. |
| 245 01 - TITLE STATEMENT |
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| Title |
Biochemical Effects of chromium, Selenium and Zinc Elements on Experimentally Diabetic Rats / |
| Statement of responsibility, etc. |
Suzan Shawky Abuel-kasem Muhamad ; Supervised by Samy Ahmed Abd El Aziz, Hassan Abdel-Halim Amer, Ismail Ibrahim Hegazy, Mohamed Abdulla Hussein.
|
| 246 03 - VARYING FORM OF TITLE |
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| Title proper/short title |
التأثيرات الكيميائية الحيوية لعناصر الكروم والسلينيوم والزنك على الفئران المصابة بداء السكري تجريبيأ |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Cairo University |
| Date of publication, distribution, etc. |
2018. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
213 p. : |
| Dimensions |
26 cm. |
| 500 ## - GENERAL NOTE |
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| General note |
Thesis (Ph.D.) - Cairo University. Faculty of Veterinary Medicine. Department of Biochemistry and Chemistry of Nutrition.
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| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc |
Includes bibliographical references.
|
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
The present work was done to elucidate the possible protective and antioxidant effect of chromium chloride (CrCl) (500 mg/k.g.), sodium selenite (SeNa) (1.5 mg/k.g.) and Zinc sulphate (ZnSO4) (54 mg/k.g.) supplementation in streptozotocin induced diabetic rats. Oral administration of both Cr and Zn as well as intraperitoneal injection of Se at concentrations of 500, 54 and 1.5 mg/kg b.w. daily, respectively for 8 weeks showed a significant decrease in fasting blood glucose, total cholesterol (TC), triacylglycerols (TG), low density lipoprotein (LDL-C) and thiobarbituric acid reactive substances. The treatment also resulted in a significant increase in plasma C-peptide, blood reduced glutathione (GSH) and superoxide dismutase (SOD) as well as gene expression of heart glucose transporter 4 (GLUT4) of diabetic rats. Also, the results clearly suggest that the trace elements treated groups may effectively normalize the body weight as well as high density lipoprotein (HDL-C) in streptozotocin induced-diabetes. The trace elements exerted rapid protective effects against lipid peroxidation by scavenging of free radicals there by reducing the risk of diabetic complications. The effect was more pronounced by Cr supplementation as compared with Se and Zn supplementation.
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| 546 ## - LANGUAGE NOTE |
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| Language note |
Text in English, abstracts in English and Arabic.
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| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| 9 (RLIN) |
4554 |
| Topical term or geographic name as entry element |
Trace elements. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
4555 |
| Personal name |
Amer, Hassan Abdel-Halim, |
| Relator term |
Supervisor |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
4556 |
| Personal name |
Abd El Aziz, Samy Ahmed, |
| Relator term |
Supervisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Koha item type |
Theses |
| Item part |
Faculty of Pharmacy كلية الصيدلة |
