Antibacterial Effect of Metronidazole Nanoparticles on Porphyromonas Gingivalis in Vitro / (Titelsatznr. 59395)
[ MARC ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02855nam a22002537a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 180910s2014 ua ||||g b|| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | SOUL |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of original | ara |
| 082 40 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Edition number | 21 |
| Classification number | 617.632 |
| Item number | A S |
| 100 #1 - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 4696 |
| Personal name | Shehab El-Din, Wessam Ibrahim. |
| 245 01 - TITLE STATEMENT | |
| Title | Antibacterial Effect of Metronidazole Nanoparticles on Porphyromonas Gingivalis in Vitro / |
| Statement of responsibility, etc. | Wessam Ibrahim Shehab El-Din ; Supervised by Azza Ezz Elarab, Ashraf Soror, Enas El-Gendy. |
| 246 03 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثير الجسيمات النانونية للمترونيدازول كمضاد للبكتيريا على البورفيروموناس جنجيفالس فى المختبر |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Cairo University. Faculty Of Oral and Dental Medicine. Department Of Oral Medicine and Periodontology. |
| Date of publication, distribution, etc. | 2014. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | vi, 2, 116 Leaves : |
| Dimensions | 30 cm. |
| Other physical details | ill. ; |
| 500 ## - GENERAL NOTE | |
| General note | Thesis (M.Sc.) - Cairo University. Faculty Of Oral and Dental Medicine. Department Of Fixed Prosthodontics. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographical references. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background & Objective: Metronidazole has played an important role in anaerobic-related infections. It is used clinically to treat gingivitis, acute necrotizing ulcerative gingivitis, chronic periodontitis and aggressive periodontitis. The newly used nanoparticles loaded with the antibiotics have been introduced in the treatment of many infections. The aim of the present study was to compare between the antibacterial effect of silver nanoparticles, metronidazole and metronidazole carried on silver nanoparticles on Porphyromonas Gingivalis (P.gingivalis) in vitro. Materials and Methods: Minimal inhibitory concentration (MIC) for the silver nanoparticles, metronidazole and the combined use of nanoparticles and metronidazole were determined. Tube dilution methods were performed and weighted in an analytical balance. Results: metronidazole loaded on Silver Nanoparticles was the most efficacious with a MIC of 0.0625 μg/ml while MIC was 0.125 µg/ml for metronidazole and 1 μg/ml for silver nanoparticles. In group III (metronidazole loaded on Silver Nanoparticles) the reduction in number of P.gingivalis was significantly greater than two other groups. Conclusion: Silver nanoparticles could have a synergistic effect with metronidazole, controlled release of metronidazole increases its effect in metronidazole loaded on silver nanoparticles group and metronidazole has an effective antimicrobial activity compared to silver nanoparticles at low concentration. |
| 546 ## - LANGUAGE NOTE | |
| Language note | Text in English, abstract in English & Arabic. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4697 |
| Topical term or geographic name as entry element | Surgery, Oral. |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 4698 |
| Personal name | Soror, Ashraf, |
| Relator term | Supervisor |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 4699 |
| Personal name | El-Gendy, Enas, |
| Relator term | Supervisor |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | Cairo University. |
| Subordinate unit | Faculty Of Oral and Dental Medicine. |
| -- | Department Of Oral Medicine and Periodontology. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Theses |
| Item part | Faculty of Dentistry كلية طب الأسنان |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent location | Current location | Shelving location | Date acquired | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 6october | 6october | 1208 | 2018-12-23 | 617.632 A S | SOULE208TH0752 | 2021-08-25 | 2018-12-23 | Theses |