Includes bibliographical references (p. 447-448) and index.

Introduction to toxicology : the necessity of measurement -- Normality : definition and maintenance -- Determination of toxicity : the basic principles -- Determination of toxicity : in vitro and alternatives -- Safety pharmacology -- Determination : general and reproductive toxicology -- Determination : genotoxicity and carcinogenicity -- Determination : dermal toxicity : sensitisation, irritation, and corrosion --

Determination : environmental toxicology and ecotoxicology -- Interpretation : basic principles -- Interpretation : different data types -- Prediction of hazard -- Background to risk due to toxicity -- Risk assessment in practice and setting exposure limits -- Risk assessment and management in the workplace -- Risk assessment : carcinogenicity, the environment, evolution, and overview of risk assessment -- Evaluation of specific classes of chemical -- The future of toxicity testing and risk assessment.