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Transdermal and topical drug delivery [[Book] :]principles and practice / Heather A.E. Benson, Adam C. Watkinson.

Von: Benson, Heather A.E.
Mitwirkende(r): Benson, Heather A. E | Watkinson, Adam C.
Materialtyp: materialTypeLabelBuchVerlag: Hoboken, N.J. : Wiley, c2012Beschreibung: xv, 446 p. : ill. ; 25 cm.ISBN: 9780470450291 ; 0470450290 .Schlagwörter: Transdermal medication | Drug delivery systems | Skin absorption | Administration, Cutaneous | Administration, Topical | Drug Delivery Systems -- methods | Skin AbsorptionDDC-Klassifikation: 615 .19
Inhalte:
Current science, skin permeation, and enhancement approaches -- Skin structure, function, and permeation -- Passive skin permeation enhancement -- Electrical and physical methods of skin penetration enhancement -- Clinical applications of transdermal iontophoresis -- In vitro skin permeation methodology -- Skin permeation assessment: tape stripping -- Skin permeation: microdialysis -- Skin permeation: spectroscopic methods -- Skin permeation assessment in man: in vitro-in vivo correlation -- Risk assessment -- Topical and transdermal product development -- Overview of product development from concept to approval -- Regulatory aspects of drug development for dermal products -- Toxicological and pre-clinical considerations for novel excipients and new chemical entities -- Topical product formulation development -- Transdermal product formulation development -- Sensitivity and irritation testing -- New product development for transdermal drug delivery: understanding the market opportunity -- Transdermal and topical drug delivery today -- Current and future trends: skin diseases and treatment.
Zusammenfassung: "By understanding the mechanisms by which compounds cross the skin, it becomes possible to devise means for improving drug delivery. Providing an overview of the current science in drug and cosmetic application to and through the skin, Topical and Transdermal Drug Delivery includes treatment of skin conditions, skin permeation, and enhancement and measurement of skin permeation. The book provides pharmaceutical scientists, skin product development experts, and those in the cosmetic and personal care industry with practical knowledge and insight into future product development"--Provided by publisher.
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Includes bibliographical references and index.

Current science, skin permeation, and enhancement approaches -- Skin structure, function, and permeation -- Passive skin permeation enhancement -- Electrical and physical methods of skin penetration enhancement -- Clinical applications of transdermal iontophoresis -- In vitro skin permeation methodology -- Skin permeation assessment: tape stripping -- Skin permeation: microdialysis -- Skin permeation: spectroscopic methods -- Skin permeation assessment in man: in vitro-in vivo correlation -- Risk assessment -- Topical and transdermal product development -- Overview of product development from concept to approval -- Regulatory aspects of drug development for dermal products -- Toxicological and pre-clinical considerations for novel excipients and new chemical entities -- Topical product formulation development -- Transdermal product formulation development -- Sensitivity and irritation testing -- New product development for transdermal drug delivery: understanding the market opportunity -- Transdermal and topical drug delivery today -- Current and future trends: skin diseases and treatment.

"By understanding the mechanisms by which compounds cross the skin, it becomes possible to devise means for improving drug delivery. Providing an overview of the current science in drug and cosmetic application to and through the skin, Topical and Transdermal Drug Delivery includes treatment of skin conditions, skin permeation, and enhancement and measurement of skin permeation. The book provides pharmaceutical scientists, skin product development experts, and those in the cosmetic and personal care industry with practical knowledge and insight into future product development"--Provided by publisher.

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