Pharmaceutical statistics practical and clinical applications / [[Book] :]
Sanford Bolton.
- 3rd ed.
- New York : M. Dekker, c1997.
- xiv, 737p. : ill. ; 24 cm.
- Drugs and the pharmaceutical sciences ; v. 80 .
Includes bibliographical references and index.
Basic definitions and concepts -- Data graphics -- Introduction to probability : the binomial and normal probability distributions -- Choosing samples -- Statistical inference : estimation and hypothesis testing -- Sample size and power -- Linear regession and correlation -- Analysis of variance -- Factoral designs -- Transformations and outliers -- Experimental design in clinical trials -- Quality control -- Validation -- Consumer testing -- Nonparametric methods -- Optimiaztion techniques -- Appendix 1. Some properties of the variance -- Appendix 2. Comparison of slopes and testing of linearity : determination of relative potency -- Appendix 3. Multiple regression -- Appendix 4. Tables -- Appendix 5. Outlier tests and chemical assays -- Appendix 6. Should a single unexplained failing assay be reason to reject a batch? -- Answers to exercises -- Index.