000			03959pam a22003254a 4500
005			20150712005519.0
008			041115s2005 njua af 001 0 eng
010			_a2004027077
020			_a0471213845
040			_aDLC _cDLC _dYDX _dUKM _dBAKER _dCUN
042			_apcc
050	0	0	_aRM301.25 _b.D784 2005
082			_a615.19
084			_a615.19 _bGD
100	1		_aGad ,Shayne Cox.
245	1	0	_aDrug discovery handbook _h[Book /] _cedited by Shayne Cox Gad.
260			_aHoboken, N.J. : _bWiley-Interscience/J. Wiley, _cc2005.
300			_axix, 1471 p. : _bill. ; _c25 cm.
504			_aIncludes bibliographical references and index.
505	0		_aIntroduction: Drug discovery in the 21st century / Shayne Cox Gad -- Natural products / Charles B. Spainhour -- Cancer cell proteomics using molecular aptamers / Weihong Tan ... [et al.] -- Molecular similarity methods and QSAR models as tools for virtual screening / J�rgen Bajorath -- Systems biology: applications in drug discovery / Sean Ekins ...[et al.] -- High throughput flow cytometry / Larry A. Sklar ... [et al.] -- Combining NMR spectral information with associated structural features to form computationally nonintensive, rugged, and objective models of biological activity / Richard D. Beger, Dan A. Buzatu, and Jon G. Wilkes -- Using Microsoft Excel as a laboratory data management tool / A. Erik Rubin, Mark F. Russo, and William Neil -- Age of regulation / Sandy Weinberg and Gerald J. Whartenby -- Simultaneous screening of multiple cell lines using the CellCard system / Oren E. Beske -- Protein X-ray crystallography in drug discovery / Peter Nollert ...[et al.] -- Biological and chemistry assays available during drug discovery and developability assessment / Duane B. Lakings -- Strategies and methods in monitoring and targeting protein-protein interactions / Arianna Loregian and Giorgio Pal?u -- High-throughput screening: evolution of technology and methods -- Martyn N. Banks ... [et al.] -- Metal-enhanced fluorescence: application to high-throughput screening and drug discovery / Kadir Aslan .. [et al,] -- Methods for the design and analysis of replicate-experiment studies to establish assay reproducibility and the equivalence of two potency assays / Brian J. Eastwood ... [et al.] -- Coupled luminescent methods in drug discovery: 3-minute assays for cytotoxicity and phosphatase activity / Michael J. Corey and Robert J. Kinders -- Design and pharmaceutical applications of prodrugs / Tomi J�arvinen ... [et al.] -- GABA and glutamate receptor ligands and their therapeutic potential in CNS disorders / Ulf Madsen ... [et al.] -- Cardiac sarcolemmal ATP-sensitive potassium channel antagonists: novel ischemia-selective antiarrhythmic agents / George E. Billman -- Factors influencing the efficacy of mediator-specific anti-inflammatory, glucocorticoid, and anticoagulant therapies for sepsis / Peter C. Minneci ... [et al.] -- Combinatorial chemistry in the drug discovery process / Nathan T. Ross, Brian R. McNaughton, and Benjamin L. Miller -- Herbal medicines and animal models of gastrointestinal diseases / C.H. Cho and J.K.S. Ko -- Endocrine and metabolic agents / Brian L. Furman -- Respiratory viruses / Paul D. Olivo -- Strategies in the design of antiviral drugs / Erik De Clercq and Piet Herdewijn -- Protein kinase inhibitors in drug discovery / Keykavous Parang and Gongqin Sun -- RNA-based therapies / Steve Pascolo -- Novel imaging agents for molecular MR imaging of cancer / Dmitri Artemov and Zaver M. Bhujwalla -- Targets and approaches for cancer drug discovery / Susan L. Mooberry.
521			_aAll Ages.
650		0	_aDrugs _xResearch _vHandbooks, manuals, etc.
650		0	_aDrug development _vHandbooks, manuals, etc.
650		0	_aDrugs _xDesign _vHandbooks, manuals, etc.
650		0	_aPharmaceutical chemistry _vHandbooks, manuals, etc.
700	1		_aGad, Shayne C., _d1948-
001			0000026379
003			0000
942			_cBK
999			_c53986 _d53986