000 02969cam a22003854a 4500
005 20150712005523.0
008 070809s2008 nyua b 001 0 eng
020 _a0824758099 (hb : alk. paper)
040 _aDNLM/DLC
_beng
_cDLC
_dDLC
042 _apcc
060 1 0 _aW1
_bAP
060 1 0 _aQV 744
_bP923 2008
082 0 0 _a615.19
_222
084 _a615.19
_bAP
100 1 _aAdeyeye ,Moji C.
245 1 0 _aPreformulation solid dosage form development
_h[[Book] /]
_cMoji C. Adeyeye, Harry G. Brittain.
260 _aNew York :
_bInforma Healthcare USA,
_c2008.
300 _aviii, 596 p. :
_bill. ;
_c24 cm.
440 0 _aDrugs and the pharmaceutical sciences ;
_v178
504 _aIncludes bibliographical references and index.
505 0 _aAccelerating the course of preliminary-preformulation through prediction of molecular physical properties and integrated analytical data management / Robert S. DeWitte, Michel Hachey, and Harry G. Brittain -- Prediction of crystallographic characteristics / Steve Spanton -- Salt selection for pharmaceutical compounds / Sherif I. Badawy, Miriam K. Franchini, and Munir A. Hussain -- Intelligent preformulation design and predictions using artificial neural networks / Nkere K. Ebube -- Developing a profile of the active pharmaceutical ingredient / Harry G. Brittain -- Particle morphology and characterization in preformulation / Alan Rawle -- Preparation and identification of polymorphs and solvatomorphs / Harry G. Brittain -- X-ray diffraction methods for the characterization of solid pharmaceutical materials / Jean Blachere and Harry G. Brittain -- Spectroscopic methods for the characterization of drug substances / Harry G. Brittain -- Thermal analysis and calorimetric methods for the characterization of new crystal forms / Dennette Murphy Shelley Rabel -- Solubility methods for the characterization of new crystal forms / Harry G. Brittain -- Overview of the solid dosage form preformulation program / Harry G. Brittain -- Drug-excipient interactions appropriate to solid dosage forms / Moji Christianah Adeyeye -- Methods for the determination of the physical and chemical stability of a new solid dosage form / Harry G. Brittain -- Dissolution testing / Chuck Collins and George Wong -- Structure, content, and format of the preformulation report / Ram N. Gidwani -- Significance of drug substance physicochemical properties in regulatory quality by design / Sau Lawrence Lee, Andre S. Raw, and Lawrence Yu.
521 _aAll age.
650 0 _aSolid dosage forms.
650 0 _aDrug development.
650 0 _aPharmaceutical chemistry.
650 1 2 _aChemistry, Pharmaceutical.
650 2 2 _aDosage Forms.
650 2 2 _aPharmaceutical Preparations
_xchemical synthesis.
700 1 _aBrittain, H. G.
700 1 _aAdeyeye, Moji C.
856 4 2 _3Publisher description
_uhttp://www.loc.gov/catdir/enhancements/fy0740/2007033181-d.html
001 0000066036
003 0000
942 _cBK
999 _c54329
_d54329