000			02914cam a22003974a 4500
005			20150712005541.0
008			110510s2012 njua b 001 0 eng
020			_a9780470450291
020			_a0470450290
040			_aDNLM/DLC _beng _cDLC _dYDX _dBTCTA _dNLM _dYDXCP _dCDX _dBDX _dMMU _dDLC
042			_apcc
060	1	0	_aWB 340 _bB T
060	0	0	_a2012 A-903
082	0	0	_a615 .19 _223
084			_a615 .19 _bB T
100	1		_aBenson, Heather A.E
245	1	0	_aTransdermal and topical drug delivery _h[[Book] :] _bprinciples and practice / _cHeather A.E. Benson, Adam C. Watkinson.
260			_aHoboken, N.J. : _bWiley, _cc2012.
300			_axv, 446 p. : _bill. ; _c25 cm.
504			_aIncludes bibliographical references and index.
505	0		_aCurrent science, skin permeation, and enhancement approaches -- Skin structure, function, and permeation -- Passive skin permeation enhancement -- Electrical and physical methods of skin penetration enhancement -- Clinical applications of transdermal iontophoresis -- In vitro skin permeation methodology -- Skin permeation assessment: tape stripping -- Skin permeation: microdialysis -- Skin permeation: spectroscopic methods -- Skin permeation assessment in man: in vitro-in vivo correlation -- Risk assessment -- Topical and transdermal product development -- Overview of product development from concept to approval -- Regulatory aspects of drug development for dermal products -- Toxicological and pre-clinical considerations for novel excipients and new chemical entities -- Topical product formulation development -- Transdermal product formulation development -- Sensitivity and irritation testing -- New product development for transdermal drug delivery: understanding the market opportunity -- Transdermal and topical drug delivery today -- Current and future trends: skin diseases and treatment.
520			_a"By understanding the mechanisms by which compounds cross the skin, it becomes possible to devise means for improving drug delivery. Providing an overview of the current science in drug and cosmetic application to and through the skin, Topical and Transdermal Drug Delivery includes treatment of skin conditions, skin permeation, and enhancement and measurement of skin permeation. The book provides pharmaceutical scientists, skin product development experts, and those in the cosmetic and personal care industry with practical knowledge and insight into future product development"--Provided by publisher.
521			_aAll age.
650		0	_aTransdermal medication.
650		0	_aDrug delivery systems.
650		0	_aSkin absorption.
650			_aAdministration, Cutaneous.
650			_aAdministration, Topical.
650			_aDrug Delivery Systems _xmethods.
650			_aSkin Absorption.
700	1		_aBenson, Heather A. E.
700	1		_aWatkinson, Adam C.
001			0000086981
003			0000
942			_cBK
999			_c55653 _d55653