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008 130607s2014 ne ab g b 001 0 eng d
020 _a9789400771956
020 _a9400771959 (cased)
041 0 9 _aeng
082 0 4 _a616.02774
_223
_bA S
100 1 _91888
_aAl-Rubeai, Mohamed
245 1 0 _aStem cells and cell therapy /
_cMohamed Al-Rubeai, Mariam Naciri, editors.
260 _anew york :
_bspringer ;
_c2014 .
265 _aاقرأ للنشر و التوزيع
300 _aviii, 189 p. :
_bill. (black and white, and col.), 1 map (col.) ;
_c25 cm.
490 1 _aCell engineering ;
_vv. 8
504 _aIncludes bibliographical references and index.
505 0 _aUse of Human Embryonic Stem Cells in Therapy -- Human Neural Stem Cell-based Cell- and Gene-therapy for Neurological Diseases -- Vascular Stem Cell Therapy -- Bioprocessing of Human Pluripotent Stem Cells for Cell Therapy Applications -- Blood Cell Bioprocessing: The Haematopoietic System and Current Status of In-vitro Production of Red Blood Cells -- Bioprocessing Challenges Associated with the Purification of Cellular Therapies -- Separation Technologies for Stem Cell Bioprocessing.
520 _aWith the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues.?The features of stem cells may provide treatment for some incurable diseases with some therapies are already in clinics, particularly those from adult stem cells. Some treatments will require large number of cells and may also require multiple doses, generating a growing demand for generating and processing large numbers of cells to meet the need of clinical applications. With this in mind, our aim is to provide a book on the subject of stem cells and cell therapy for researchers and students of cell biotechnology, bioengineering and bioproduction. This book is exceptional as it teaches researchers stem cells and cell therapy in that it covers the concepts and backgrounds necessary so that readers get a good understanding of the production of stem cells. The book covers three topics: The basics of stem cells and cell therapy, the use of stem cells for the treatment of human diseases, and stem cell processing. It includes chapters on neural and vascular stem vascular stem cell therapy, expansion engineering of embryonic stem cells, stem cell based production of blood cells and separation technologies for stem cells and cell therapy products. It is an informed and informative presentation of what modern research, science and engineering have learned about stem cells and their production and therapies. Addressing both the medical and production issues, this book is an invaluable contribution to having an academic and industrial understanding with respect to R&D and manufacturing of clinical grade stem cells.
650 1 4 _aStem Cell Transplantation
_xmethods
_91890
700 1 _aNaciri, Mariam
_eeditor.
_91891
830 0 _aCell engineering ;
_vv. 8.
942 _2ddc
_cBK
_iFOE
_6FOE